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You don't have to take (land)tours in Istanbul, the city is very modern with good communications. However as a tourist with kids you'll more than likely keep to a smaller area, the Golden Horn have pretty much everything you need to see with the modern Taksim to the north. That should keep you going for at least a week. But do take a boat tour on the Bosphorus, you find them everywhere. Outside of Istanbul I'm not quite sure however.
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