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A new coronavirus treatment being developed at Tel Aviv’s Ichilov Medical Center has successfully completed phase 1 trials and appears to have helped numerous moderate-to-serious cases of COVID-19 quickly recover from the disease, the hospital said Friday.
Hailing a “huge breakthrough,” the hospital said Prof. Nadir Arber’s EXO-CD24 substance had been administered to 30 patients whose conditions were moderate or worse, and all 30 recovered — 29 of them within three to five days.
The medicine fights the cytokine storm — a potentially lethal immune overreaction to the coronavirus infection that is believed to be responsible for much of the deaths associated with the disease.
It uses exosomes — tiny carrier sacs that shuttle materials between cells — to deliver a protein called CD24 to the lungs, which Arber has spent decades researching.
Small study, but it is very promising
The Israelis are always on the forefront of science, medicine and technology
Study: Respiratory failure in COVID-19 usually not driven by cytokine storm
Findings indicate anti-inflammatory drugs likely to benefit only a fraction of people with severe disease
Study: Respiratory failure in COVID-19 usually not driven by cytokine storm
Findings indicate anti-inflammatory drugs likely to benefit only a fraction of people with severe disease
Study: Respiratory failure in COVID-19 usually not driven by cytokine storm
Findings indicate anti-inflammatory drugs likely to benefit only a fraction of people with severe disease
If I get sick, maybe I'll be part of the fraction benefitting. Maybe the fraction of people benefitting from this treatment will be 99/100. That's a fraction. Pretty good fraction.
Doesn't matter if it's 1/99 or 99/100. One life saved is a good thing, right?
Ivermectin studies are showing promise. My household has benefited from being prescribed Ivermectin. But people still claim that it's not 100% effective.
It's almost as if some people would rather wear masks, isolate, social distance, etc, forever than accept life's risks.
It certainly looks promising. It seems like it's more of a case study/series at this point (it was observed to cure 29/30 people), so would need to go through clinical trials. But it is definitely a great start, and the fact that it worked so well means that there is likely some key finding in the treatment to get us one step closer (even if it were not prove quite as successful in a large clinical trial). I hope that the NIH, researchers, pharm, and tech companies start to investigate this for clinical trials.
I'm happy to hear that a treatment is available. And I'm not surprised that Israel developed it. Israelis were always on the forefront of research and development. Heck, ICQ---my username says it all, doesn't it ---was developed in Israel by Mirabilis. And so was Windows XP . So who's to say Israel wouldn't be equally skilled at developing a Covid treatment.
That said, a treatment was already available since early on: Hydroxychloroquine. I can't understand for the life of me why the Powers That Be are so fervent about keeping it out of the general public's hands.
Last edited by MillennialUrbanist; 02-06-2021 at 07:53 PM..
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