After 40,000 failed trials and "painstakingly slow progress," scientists have solved a puzzle that stumped AIDS researchers for more than 20 years—and their findings could help develop more effective HIV drugs. The researchers at Harvard and Imperial College London grew a crystal that for the first time made visible the structure of integrase, the enzyme targeted by many newer HIV drugs, Reuters reports.
Scientists Make Enzyme Integrase Visible to Crack HIV AIDS Drug Puzzle