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Old 08-14-2011, 10:04 AM
 
13,511 posts, read 19,284,780 times
Reputation: 16581

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Quote:
Originally Posted by nana053 View Post
Where do you get these links and this history?

The vaccine when I was a child was the inactivated or killed vaccine which was developed by Salk in 1955. The oral polio vaccine did cause some cases of polio, but it was not the cause of the epidemic. The oral polio vaccine did cause some 8 to 10 cases per year which is why it was removed in the US, but it was removed in 2000, not in 1963. And, the oral polio vaccine is still used in countries where polio is more of a threat. Polio was eliminated in the US in 1991, but can still be imported from Africa and Asia. The routine vaccination in the US though is the IPV or inactivated vaccine that was developed in 1988 and became routine in 1997. It is a much stronger version of the original IPV.

The epidemic struck 60,000 children per year. The vaccination (mostly the OPV) wiped out the disease except for those struck down by the vaccine which is why the change to the IPV was made. Striking 6 to 10 children per year is certainly unacceptable now, but saving 60,000 per year made the risk reasonable back in the 50s and 60s.
Where did YOU get these links and history???I did not say oral polio vaccine was removed in 1963...I said the "contaminated" vaccine was removed....and did you even dare to look up SV40??...obviously not!!!
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Old 08-14-2011, 12:04 PM
 
17,183 posts, read 22,921,959 times
Reputation: 17478
Quote:
Originally Posted by purehuman View Post
Where did YOU get these links and history???I did not say oral polio vaccine was removed in 1963...I said the "contaminated" vaccine was removed....and did you even dare to look up SV40??...obviously not!!!
Since my background is mathematics and science, I look for links to actual science.

SV40 is linked to cancer, btw, not to the incidence of polio caused by the Salk Vaccine. Your assertion was that these children had gotten polio from the vaccine which is simply not true of those who contracted polio during the epidemic in large numbers.

SV40, genetic polymorphism and mesothelioma. pathological and epidemiological evidence. - Travel Doctor Online

Quote:
Studies researching SV40 DNA in MM tissue observed a wide range of prevalences (0% to 70%); causes of variability were not convincingly identified. An association of MM with SV40 was suggested but confounding factors and biases were not considered. Cohort studies on humans inoculated with contaminated vaccines did not show an increased incidence but their statistical power was limited. Diffusion of SV40 in humans is linked to polio vaccines produced in 1955-63 from SV40-infected monkeys. A 11-12% prevalence of SV40 in adults were reported in the USA, 2-6% in Europe and Africa. The age pattern of MM does not suggest a cohort effect related to contaminated vaccines.
Quote:
Association of SV40 with human MM is suggested from laboratory observations but still lacks confirmation in well designed epidemiological studies. Other putative co-factors in MM occurrence are mutations in genes involved in repair of damage caused by asbestos, notably DNA-repair genes. Preliminary observations are available but epidemiological studies are needed to test this hypothesis.
More recent
Studies:No Evidence That SV40 is Related to Cancer - National Cancer Institute

Quote:
Studies Find No Evidence That SV40 is Related to Human Cancer

Recent studies by scientists at the National Cancer Institute (NCI), one of the National Institutes of Health, provide further evidence that exposure to simian virus 40 (SV40) is not associated with cancer in humans. Many U.S. polio vaccines administered from 1955 to1962 were accidentally contaminated with SV40 because the vaccines were grown in monkey kidney tissue. Before discovery of the virus led to changes in vaccine manufacture, millions of Americans received SV40-contaminated polio vaccines. This has been a significant public health concern, as SV40 has been shown to cause cancer in experimental animals.

Studies investigating the possible connection between SV40 and human cancer have been inconclusive. For example, some laboratories have reported the detection of minute quantities of SV40 DNA in human tumors while others have not been able to replicate these results.
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