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It depends on what you're making, how much wine you need, and how integral the wine is to the finished dish. For instance, if you're making beef burgundy, you kinda need wine or you won't be eating beef burgundy. But if you're dumping wine into a stew, you can get by with a substitution with only a slight alteration in the flavor.
Broth can be substituted sometimes. Red or white grape juice might work. So might plain water.
I've kept wine for cooking purposes only in the fridge for months; as long as what I'm making doesn't have a lot of wine in it, the flavor of the dish isn't really compromised all that much by old wine. Another idea is to go ahead and buy a bottle of wine and freeze the leftovers in ice cube trays for your next use. Or buy a four-bottle carton of small bottles and have fresh wine on hand still in the bottle.
I take it you won't drink the leftovers ... because leftover wine is rarely an issue at my house.
Most liquor stores sell tiny bottles of wine like the kind you get on an airplane. costs about $2.00. That's what I do if I don't have any wine in the house and I only need a little bit for a recipe. One of the bottles equals about 1 cup maybe a bit less.
In some beef recipes I've seen, it'll say "1 cup beef broth plus one cup red wine or beef broth" or something like that. Or just buy those tiny bottles.
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