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Wow, this is kind of a bummer to me as a professional working with these kids. What we do know is that the brain of a child on the PDD/Autism spectrum does not seem to metabolize/process medications the same way as a typically developing brain.
Unfortunately, there's no one "sure thing" medication with an autistic child, so many of them wind up on numerous meds all at once. Then when something goes either wrong or right, it's impossible to know which of the drugs was causing the bad or good effect. It's such a trial and error process, and so frustrating to both the parents and the professionals involved.
The one good news nugget out of this report seems to be that this almost certainly eliminates the heretofore ascribed-to theory that anxiety disorders such as OCD share the same neurochemical pathway as Autism. However, they frequently co-exist.
I bet the Celexa folks are very unhappy with these results.
ITA with you. Especially the first two paragraphs.
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