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Old 02-03-2022, 10:08 AM
 
Location: As of 2022….back to SoCal. OC this time!
9,297 posts, read 4,577,093 times
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Quote:
Originally Posted by rstevens62 View Post


I cannot understand the mindset of a person who does this?!!



You would have to understand mental health, clinical depression or bipolar & psychosis to understand why somebody might commit suicide…especially somebody that seems as tho they have everything going for them.
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Old 02-03-2022, 12:56 PM
 
Location: Elsewhere
88,560 posts, read 84,755,078 times
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Quote:
Originally Posted by rstevens62 View Post
YES, YES, YES!!


I cannot understand the mindset of a person who does this?!!


How do they know what they are jumping into? What if its worse than their life was, what will they do then?


This is the ONE thing that kept me from committing suicide years ago, when I was coming off Heroin/ other drugs, I wanted to die so bad...but I could not justify going thru with it, because I could not guarantee, it would relieve any of my suffering.


Committing suicide is like jumping head first into a body of water you are unfamiliar with, (water could be only 1 ft deep!)
All they can think about is ending the pain. You are expecting a logic or thought process to be there that just doesn't exist.

I know from other of your posts that you have very specific ideas and fears about hell, demons, the afterlife and such, but not everyone else does.
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Old 02-03-2022, 01:29 PM
 
Location: colorado springs, CO
9,512 posts, read 6,099,317 times
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The reason people with great lives kill themselves, is for the same reason people with crappy lives kill themselves: They've experienced some biochemical insult to their brain. And it's probably related to a neuroimmune response. Immune-mediation is already a proven cause of mental illness, including depression, anxiety & even Schizophrenia. Their lives aren't sadder: They THINK they are sad. It's a trick of the brain.

It doesn't have anything to do with how their life is.

There are RARE suicides of passion, where extreme bereavement or catastrophe could cause someone to make a spontaneous decision & throw themselves in front of a truck but that really doesn't happen much.
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Old 02-03-2022, 01:35 PM
 
Location: State of Transition
102,203 posts, read 107,859,557 times
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Quote:
Originally Posted by coschristi View Post
The reason people with great lives kill themselves, is for the same reason people with crappy lives kill themselves: They've experienced some biochemical insult to their brain. And it's probably related to a neuroimmune response. Immune-mediation is already a proven cause of mental illness, including depression, anxiety & even Schizophrenia. Their lives aren't sadder: They THINK they are sad. It's a trick of the brain.

It doesn't have anything to do with how their life is.

There are RARE suicides of passion, where extreme bereavement or catastrophe could cause someone to make a spontaneous decision & throw themselves in front of a truck but that really doesn't happen much.
Could you explain the bolded in a bit more detail, please? It sounds like you're onto something. This sounds like valuable information. I don't know what "immune-mediation" means, though, and how it works.
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Old 02-03-2022, 03:17 PM
 
Location: colorado springs, CO
9,512 posts, read 6,099,317 times
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Quote:
Originally Posted by Ruth4Truth View Post
Could you explain the bolded in a bit more detail, please? It sounds like you're onto something. This sounds like valuable information. I don't know what "immune-mediation" means, though, and how it works.
Immune mediation basically refers to something resulting from the activity of the immune system. The immune system is mediated itself, by proteins called Cytokines. Cytokines are divided into proinflammatory cytokines or antiinflammatory cytokines & they work in a delicate balance.

Proinflammatory cytokines sound "bad" but they are "good" at their job, which involves things like stimulating the immune system to fight a foreign pathogen or attack tumors. Antiinflammatory cytokines are "good" for reducing an immune response, to prevent the development of auto-immune disease.

https://pubmed.ncbi.nlm.nih.gov/26015504/

If anything interferes with this, or causes an atypical immune response, things can go awry. Like how we heard that people with severe Covid were dying due to "cytokine storm"? Cytokine storms mean that there has been a wildly exaggerated, (or "storm") of inflammatory cytokines. The immune system has gone rogue, and the body attacks itself.

Even if the storm isn't severe & the person doesn't die; a cytokine storm can directly impact the brain, via the brain's immune cells, called Microglia. Atypical Microglia activation is found in the brains of people with Schizophrenia & there's quite a bit of evidence to show that Schizophrenia is indeed an "Immune-mediated" disorder:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4595998/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742288/

Now we are finding that depression itself is showing similar immune mediation "signatures", including that people suffering depression, ALSO have elevated levels of proinflammatory cytokines.

https://www.frontiersin.org/articles...019.01696/full

I really think there's a lot of value in researching the immune system's role in mental illness. There already are therapeutics that are considered "immunomodulatory". Instead of treating the SYMPTOMS of mental illness, we could be treating the cause & avoiding the adverse effects of the psychotropics currently used.
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Old 02-03-2022, 05:35 PM
 
Location: Texas Hill Country
23,652 posts, read 13,982,074 times
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Maybe our society pushes too much being specialists and not generalists which deprives one from considering what the options are (nutshell speaking).
Quote:
Originally Posted by Ruth4Truth View Post
But her business was law! Her beauty pageant days were over; she'd won the top award! She was done with that, and could focus on her law career. That's what makes no sense. It doesn't matter if there were younger ones coming down the pipeline. Of course there were; there always are. The winners do their stint as the figurehead for a year, then they get on with their lives.

Some become models for advertising, in which case their looks are still important, but this one had a law career and a business degree. She had some great life options, that didn't hinge on her looks at all. That's what makes no sense about her fretting about her looks. When her year as Miss USA was done, she'd be out of the public eye, no more need to think about her looks except on the ordinary level of looking presentable for career and social life.

But she was obsessed. She couldn't seem to see past the pageant scene or mentality. She became trapped by that.

Or maybe she'd set herself the goal of entering Miss Universe, and was afraid of losing, because of her age? There's been no indication so far, that she was planning to continue in the pageant "business".
Realizing that you are no longer a Goddess, that you have lost your Mount Olympus membership card can be quite a show stopper. I am still going through so many questions of the things I could do 2 or so years ago that I can't do now. Even if I wasn't doing what I was doing in my 20s, I was moving so fast on full after burners, doing things of a God but in another interpretation........and I am not there now.

So why not me, too? Well, two things, both from the way I see life. First, by now, people ought to realize that I am very fantasy driven, I live in fantasy worlds, Glinda, the good witch, all that kind of stuff.

Secondly, I have my imaginary anchors. My flight computers are working each day to find me the best fit for that day. Each morning, I have to get my cheerleader charge, a music video to propel me as being the office cheerleader, where attitude, what I say, how I pose my body, everything, works into it.

I sometimes worry that this new me, that is increasing in leaps and bounds, is too much out there, too much a fantasy in reality, but, long story short of it, it pleases me to be Godlike.

BUT.....what happens when you can no longer interpret the world in your own view, to be able to march to your own drummer, ........ and the world around you thinks it is okay to see reality just like they do, why can't everyone see it that way?

Just like what I said a few weeks ago about stuffed animals, of how others might see that as unhealthy, but they have no concept of what a world without a SO is. (just an example, not a point of discussion)

Do not see the others should see the world as one does without considering all the things in one's world.
Quote:
Originally Posted by rstevens62 View Post
YES, YES, YES!!

I cannot understand the mindset of a person who does this?!!

How do they know what they are jumping into? What if its worse than their life was, what will they do then?

This is the ONE thing that kept me from committing suicide years ago, when I was coming off Heroin/ other drugs, I wanted to die so bad...but I could not justify going thru with it, because I could not guarantee, it would relieve any of my suffering.

Committing suicide is like jumping head first into a body of water you are unfamiliar with, (water could be only 1 ft deep!)
Perhaps. On the other hand, does one's life experiences block what is trying to be explained?

I ran into this problem few weeks ago when they asked me about describing my vertigo not as dizziness and I couldn't......because all my flight and dive training had it known to me as exactly that.........

.........and as a diver, I have plenty of experience of being in unknown waters.

I suppose that part of life goes both ways. That is, if I have something coming up on the schedule, it is eventually, "Step up to bat and whatever happens, I will handle it, figure it out.".....

.......but I suppose to that approach of handling things, there is the possible situation of no way back.

Besides, while there is this from Buffy TVS (The Wish):

Anyanka: You trusting fool! How do you know the other world is any better than this? Giles: Because it has to be.

The basic point of things is that sooner or later we have to step up to that particular bat (What Dreams May Come put aside for a moment).

Last edited by TamaraSavannah; 02-03-2022 at 06:16 PM..
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Old 02-03-2022, 06:31 PM
 
3,933 posts, read 2,190,360 times
Reputation: 9996
Quote:
Originally Posted by coschristi View Post
Immune mediation basically refers to something resulting from the activity of the immune system. The immune system is mediated itself, by proteins called Cytokines. Cytokines are divided into proinflammatory cytokines or antiinflammatory cytokines & they work in a delicate balance.

Proinflammatory cytokines sound "bad" but they are "good" at their job, which involves things like stimulating the immune system to fight a foreign pathogen or attack tumors. Antiinflammatory cytokines are "good" for reducing an immune response, to prevent the development of auto-immune disease.

https://pubmed.ncbi.nlm.nih.gov/26015504/

If anything interferes with this, or causes an atypical immune response, things can go awry. Like how we heard that people with severe Covid were dying due to "cytokine storm"? Cytokine storms mean that there has been a wildly exaggerated, (or "storm") of inflammatory cytokines. The immune system has gone rogue, and the body attacks itself.

Even if the storm isn't severe & the person doesn't die; a cytokine storm can directly impact the brain, via the brain's immune cells, called Microglia. Atypical Microglia activation is found in the brains of people with Schizophrenia & there's quite a bit of evidence to show that Schizophrenia is indeed an "Immune-mediated" disorder:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4595998/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742288/

Now we are finding that depression itself is showing similar immune mediation "signatures", including that people suffering depression, ALSO have elevated levels of proinflammatory cytokines.

https://www.frontiersin.org/articles...019.01696/full

I really think there's a lot of value in researching the immune system's role in mental illness. There already are therapeutics that are considered "immunomodulatory". Instead of treating the SYMPTOMS of mental illness, we could be treating the cause & avoiding the adverse effects of the psychotropics currently used.
Thank you for your links - very interesting research!
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Old 02-03-2022, 06:48 PM
 
64 posts, read 46,618 times
Reputation: 155
I came across this book and am reading it now to get some better insights into suicide, depression, anxiety. It’s a very good well written book on the subject imo.

https://www.npr.org/2017/08/02/54097...made-maddy-run
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Old 02-03-2022, 10:34 PM
 
17,874 posts, read 15,939,379 times
Reputation: 11660
I thought Miss USA was very early 20s, not late 20s. Oh well

RIP Cheslie, and condolences to family
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Old 02-03-2022, 10:43 PM
 
Location: PNW
7,521 posts, read 3,236,257 times
Reputation: 10687
Quote:
Originally Posted by coschristi View Post
Immune mediation basically refers to something resulting from the activity of the immune system. The immune system is mediated itself, by proteins called Cytokines. Cytokines are divided into proinflammatory cytokines or antiinflammatory cytokines & they work in a delicate balance.

Proinflammatory cytokines sound "bad" but they are "good" at their job, which involves things like stimulating the immune system to fight a foreign pathogen or attack tumors. Antiinflammatory cytokines are "good" for reducing an immune response, to prevent the development of auto-immune disease.

https://pubmed.ncbi.nlm.nih.gov/26015504/

If anything interferes with this, or causes an atypical immune response, things can go awry. Like how we heard that people with severe Covid were dying due to "cytokine storm"? Cytokine storms mean that there has been a wildly exaggerated, (or "storm") of inflammatory cytokines. The immune system has gone rogue, and the body attacks itself.

Even if the storm isn't severe & the person doesn't die; a cytokine storm can directly impact the brain, via the brain's immune cells, called Microglia. Atypical Microglia activation is found in the brains of people with Schizophrenia & there's quite a bit of evidence to show that Schizophrenia is indeed an "Immune-mediated" disorder:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4595998/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742288/

Now we are finding that depression itself is showing similar immune mediation "signatures", including that people suffering depression, ALSO have elevated levels of proinflammatory cytokines.

https://www.frontiersin.org/articles...019.01696/full

I really think there's a lot of value in researching the immune system's role in mental illness. There already are therapeutics that are considered "immunomodulatory". Instead of treating the SYMPTOMS of mental illness, we could be treating the cause & avoiding the adverse effects of the psychotropics currently used.
What are these therapeutics that are "immunomodulatory?" I want to get into this subject with my shrink as I have only ever taken anti depressants very short periods of time. I have depression that is associated with PTSD and a horrific accident. But, also my health status has changed in the fifteen years since the accident. Thanks in advance.

I think I will focus on an anti inflammatory diet (all roads lead to...)...

Last edited by Wile E. Coyote; 02-03-2022 at 11:09 PM..
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