Break Through In Producing Insulin Cells: A Cure? (Metformin, work)

[markg91359]

Type 1 diabetes occurs when the pancreas stops producing insulin or produces inadequate amounts of insulin.

One idea that has been researched in recent years is the idea of creating insulin producing cells and injecting them into the pancreas. This approach has always been limited by the fact that in the past it was necessary to gather large quantities of embryonic stem cells for this purpose. Not enough of these could ever be obtained to make this practical as a possible cure for diabetes. Now, scientists believe they have a way to produce abundant numbers of these cells.


https://uk.news.yahoo.com/cure-type-...9.html#kCTgLCP

[jambo101]

Would this technology also work for type 2s?

[legalsea]

Originally Posted by jambo101

Would this technology also work for type 2s?

I would think not. Type I the pancreas produces no insulin (hence insulin shots). Type II means that insulin is still being produced, but the cells will not absorb said insulin (insulin resistance), hence the pills (like Metformin) that make the cells accept the insulin.

However, many Type II diabetics end up with having to use insulin. The pancreas will make extra insulin to make up for the insulin resistance of the cells (if untreated), but will, I guess, 'exhaust' itself over time, harming its ability to keep producing such high levels of insulin. Perhaps in that case this technology would work.

Note: I have been waiting for 20 years for a breakthrough. Many have been advertised, none have panned out. Yet, who knows?

[JonDoeUK]

Other treatments are being looked into CLBS03 | Caladrius Research & Development - PharmaCyte Biotech, Inc.

[JonDoeUK]

Originally Posted by jambo101

Would this technology also work for type 2s?

Sadly not. However other drugs may end up helping better than current SOC TTP399 | vTv Therapeutics TTP273 | vTv Therapeutics GWPharma - Diabetes and there are clinical trials https://clinicaltrials.gov