Has anyone had the 'lisinopril cough'? (cold, blood pressure, doctor, heart)
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I had it for a very short time when I first started taking lisinopril, then it stopped. Haven't had any trouble with it at all since then, and it's been maybe 15 years or so.
The mechanism of cough is likely multifactorial. ACE inhibitors prevent the breakdown of bradykinin and substance P, resulting in an accumulation of these protussive mediators in the respiratory tract. In addition, bradykinin can stimulate the production of prostaglandin.[1] This side effect is not dose-dependent and often precludes the use of all agents within the drug class.
Cardiologist started me on lisinopril after a mild heart attack. I'm expecting it to be temporary as my normal BP isn't very elevated. Noticed a very slight cough at first, but I had dutifully read the medication leaflet so sort of expected it...was that auto suggestion or a real effect? It seems to have subsided. Hasn't been enough to bother me. A long time friend of mine has been on it for years and he does notice the cough.
One minor thing I have noticed is a runny nose; when I'm out in the cold it turns into a faucet a lot faster than it used to!
Last edited by Parnassia; 04-19-2020 at 05:43 PM..
My mom went on lisinopril as the first medication to control high blood pressure and developed a cough about a month after she first started taking it. She didn't know why she kept coughing so went to the doctor because it was getting annoying because she coughed pretty frequently. It also gave her cold-like symptoms.
She was changed over to one of the beta-blockers and has had no side effects with them outside of some drowsiness at first and her blood pressure is under control.
I don't recall exactly but the cough went away pretty quickly after she went off the lisinopril; I think it was a week or two.
My dad also was on lisinopril and had some of the coughing but it didn't bother him that much so he didn't switch medications.
I had the cough when I took it. I also got a malar rash. When I stopped taking it, the rash cleared up within a couple of months.
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