If you're looking for fish you can eat... large mouth bass and the like, I would suggest Bear Rock Lake. It is located near US 40 near Valley Grove, WV close to the PA state line.
Bear Rock Lakes Wildlife Management Area - Wikipedia, the free encyclopedia
If you want to fish for sport only, the Ohio River has catfish as big as sharks and huge carp. One of the better places to fish the river is near the Pike Island Locks and Dam north of Warwood. A West Virginia fishing license is also good (on the river only) on the Ohio side of the river.