Syracuse Hancock International Airport, located minutes from the downtown area, serves more than 200 passenger flights daily on 8 major airlines and 4 commuter lines.
Two major four-lane highways intersect Syracuse. Interstate 81, a north-south route, passes through the center of the city. Interstate 90 (the New York State Thruway), an east-west route, crosses Interstate 81 a mile north of the city.
Amtrak provides passenger rail service. Greyhound, Onondaga Coach, Syracuse & Oswego and Trailways provide intercity and interstate bus travel.
The downtown business district is bounded by Interstate 81 and Interstate 690 and is easily accessible by car. CENTRO, described as one of the nation's best mid-sized transit systems, provides bus service throughout the city on 24 routes. It also operates Call-a-Bus services for the elderly and disabled.