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The problem with your groupings is that the Mississippi River states are all so different from one another that it's hard to compare them as a group with the west coast, which as a whole is more homogenous. For example, Illinois and Mississippi, or Arkansas and Minnesota, share so little in common that it's near impossible to assess them as a group. Plus, the Mississippi River itself has such little influence on Kentucky that I question why you would place it in this grouping. Anyway, I would subdivide Group 1 into more groups, and make a splinter group for the southern states, so it at least makes more sense. I think it should be like this:
Group 1A-MN, WI
Group 1B-IL, IA, MO
Group 2A-KY, TN
Group 2B-AR, MS, LA
The only time you will see Minny and Mississippi grouped together.
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