Yes but there are already DOZENS of small towns in Italy that are Città Fantasme or ghost towns as either all the inhabitants had moved out or died off. Last summer I took (with a friend) a drive into the interior of Molise and we went to see half a dozen hill top towns and I tell you most of them had maybe a few hundred elderly residents left and it was clear that whenever the last of them dies off the city would effectively be deserted. This is because all the young people had moved away in search of a job/better life. For instance, if you ask anyone in these tiny hill top towns where did everyone go they will tell you Termoli, a beautiful seaside town in Molise that has stores, malls, movie theaters, basically all that a modern city has to offer.
Molise is beautiful and I tell you (like any other rural parts in Italy) when you drive through these towns it is like going back in time. Also, as an American I asked my Italian friend "why did they build a city here on this hill in what seems like the middle of nowhere?" The response is years ago villages were built high up to offer it's citizens protection as well as a heads up if invaders came. Also Italy was an agricultural country so the land itself was a persons source of income. Being born in America our cities got populated or grew up around a source of income which was usually factory, mining, finance (like many cities on the East Coast) etc. but never because the land offered protection. So that was extremely interesting.
Anyway click below for a list of towns in Italy that are deserted. Notice they have them in EVERY region!
Città fantasma in Italia - Wikipedia (it is in italian so use google to translate)