The usual haunts:
Bar Louie (one at GCTC and one at Edison)
blu (one on McGregor and one at GCTC)
Cru (41 and Daniels at Bell Tower)
The Joint (Cape Harbor, but has started to die out)
Dek (back streets 15th I think off 47th terrace in the cape)
Downtown is a great pub crawl:
Baccas,
City Tavern,
French Connection (late night eats and booze), Sky Bar,
H2,
Scotty's lounge,
and don't forget the
Bar Association (wine and beer only, keeps out the hard core drunks and the owner makes it like an adult day care, ask to use the hula hoop).
You also have Level and a couple other "trying to be high end" clubs whose names escape me.
Oh there is the "trio" the Cigar bar (also at GCTC), Long shot Louie's, and Top Cats (they are the "Trio" because they are all connected, but make sure you pay your tab at each place before leaving (they will let you carry beers between them, but not the "real" glasses, but plastic is ok).
Oh, there is Patio 33 and Indigo Room.
So yes, it is a massive pub crawl downtown with something for all ages.

(Also stuff to eat at too).