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Vinpocetine, an ingredient found in some dietary supplements, may be associated with adverse reproductive effects, according to a safety communication from the Food and Drug Administration (FDA).
The warning comes after the Agency reviewed a report by the National Institute of Health’s (NIH) National Toxicology Program (NTP) which evaluated the “developmental and/or reproductive toxicity of selected substances in laboratory animals.” Results showed vinopocetine decreased fetal weight and increased the chance for miscarriage in pregnant animals. As the blood levels of vinpocetine measured in the animals were similar to those reported in individuals who consumed a single dose of vinpocetine, it can be inferred that the risks would apply to humans as well.
Vinpocetine, a synthetically produced compound, is sometimes referred to as Vinca minor extract, lesser periwinkle extract, or common periwinkle extract; dietary supplements containing vinpocetine have been marketed for improving memory, focus, and energy, as well as for promoting weight loss.
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