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Well if your loved one is faced with COVID19, you can choose now between Remdesivir and Hydroxy...take your pick. A coin toss would be the best way to decide!
Well if your loved one is faced with COVID19, you can choose now between Remdesivir and Hydroxy...take your pick. A coin toss would be the best way to decide!
Not really. Hydroxychloroquine is best early in the disease because it stops the virus from infecting cells by inhibiting the attachment of the virus before it engages the ACE2 receptor. Like I said Turkey gives it to people as soon as they are diagnosed. In severe hospitalized cases many cells are already infected so it's not as effective. Remdesivir speeds recovery in hospitalized patients so if someone is so sick that they get hospitalized they get that.
The International Steering Committee formulated the recommendation in light of the evidence for hydroxychloroquine vs standard-of-care and for lopinavir/ritonavir vs standard-of-care from the Solidarity trial interim results, and from a review of the evidence from all trials presented at the 1-2 July WHO Summit on COVID-19 research and innovation.
These interim trial results show that hydroxychloroquine and lopinavir/ritonavir produce little or no reduction in the mortality of hospitalized COVID-19 patients when compared to standard of care. Solidarity trial investigators will interrupt the trials with immediate effect.
For each of the drugs, the interim results do not provide solid evidence of increased mortality. There were, however, some associated safety signals in the clinical laboratory findings of the add-on Discovery trial, a participant in the Solidarity trial. These will also be reported in the peer-reviewed publication.
This decision applies only to the conduct of the Solidarity trial in hospitalized patients and does not affect the possible evaluation in other studies of hydroxychloroquine or lopinavir/ritonavir in non-hospitalized patients or as pre- or post-exposure prophylaxis for COVID-19. The interim Solidarity results are now being readied for peer-reviewed publication.
So, from that it appears the drug does not help hospitalized patients but it is still being studied for non hospitalized patients i.e. milder cases.
I've heard some doctors talk about this. It seems that the earlier HCQ is administered, the better, as it has helped in some cases.
The synopsis is that it helps people get better who were likely to get better anyway. But it helps speed up the recovery and reduce symptoms.
Sort of like a Tamiflu for COVID.
As much as I hate to come down on the Trumper's side, I don't think it was a bad thing to give to people earlier in their course of symptoms provided their hearts were stable. However I don't know if it is really a good option when people are really sick if there are other options for the patient.
The synopsis is that it helps people get better who were likely to get better anyway. But it helps speed up the recovery and reduce symptoms.
Sort of like a Tamiflu for COVID.
As much as I hate to come down on the Trumper's side, I don't think it was a bad thing to give to people earlier in their course of symptoms provided their hearts were stable. However I don't know if it is really a good option when people are really sick if their are other options.
I too heard it wasn't that effective for someone who was quite ill and later on in their treatment.
The study was skewed. With that being said, i think it should be up to the patient's family to decide if they want the drug to be used on their loved one or not. Give them options and have them sign a waiver.
More than likely the doc will be the one managing the patient. Hopefully a doc chosen and trusted by the patient.
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