Old malaria drug hydroxychloroquine may help cure coronavirus: study (Israeli, accuse, regular)
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Now the people who need it, like people who have lupus and other diseases that are actually treated with chloroquine, are having trouble getting their prescriptions filled. If other people start getting prescriptions filled as a prophylactic measure, what are the people who actually need it to treat their existing diseases supposed to do in the meantime?
Everyone who makes this drug is gearing up increased production. I don't want anyone to not get the drugs they need, but the concept of basically stopping life as we know it for 18 months until a vaccine is available will lead to far more dire consequences for far more people.
Think of what one food shortage in a place like los angeles or new york city would result in. You think that won't happen in 18 months?
Can I vent for one minute?
Did we not spend billions and billions and billions on emergency preparedness since 9/11?
Agreed. Even where I work. We have spent tons of time and tons of money preparing for scary things since 911 and all of the ability to get this stuff done is 100% on the back of the good people working there who are making it happen... mostly, in spite of, of the management who clearly was not prepared.
Last week it took over a week to decide who was coming in and who wasn't. These plans should have been made YEARS ago and stuck to. Instead it took a week of e-mails around and around with people who just wanted to hear themselves speak and finally I think a plan was just decided by default.
This was an entirely likely thing and it actually had over a month of prep time.
In the early stages of this crisis I posted a topic asking why Africa was being spared. Even now most sub Saharan African nations have few cases, and of those they were people coming from abroad. Most Africans take this malaria medication already....so it appears to work as a prophylactic against the virus. I am optimistic. China figured this out long ago. I don’t know why the US insists on trying to recreate the wheel all the time.
Exactly what i heard from a friend from Africa. Now, could it just be a genetic trait in people of African ethnicities? I thin black people are getting covid though. Again all anecdotal...but hope.
Exactly what i heard from a friend from Africa. Now, could it just be a genetic trait in people of African ethnicities? I thin black people are getting covid though. Again all anecdotal...but hope.
India... with its population (and travelers) only has 283 cases. India is a Malaria country.
He spoke inaccurately, but that's irrelevant. For 86 years, licensed physicians have been able to prescribe hydroxychloroquine legally in this country. And that's true today.
They can prescribe it for malaria, arthritis, or COVID-19. It's perfectly legal, no questions asked.
Useful in patients that have progressive effects of the virus but not a cure or preventative.
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treatment of novel coronavirus pneumoia Abstract
At the end of December 2019, a novel coronavirus (COVID-19) caused an outbreak in Wuhan, and has quickly spread to all provinces in China and 26 other countries around the world, leading to a serious situation for epidemic prevention. So far, there is still no specific medicine. Previous studies have shown that chloroquine phosphate (chloroquine) had a wide range of antiviral effects, including anti-coronavirus. Here we found that treating the patients diagnosed as novel coronavirus pneumonia with chloroquine might improve the success rate of treatment, shorten hospital stay and improve patient outcome. In order to guide and regulate the use of chloroquine in patients with novel coronavirus pneumonia, the multicenter collaboration group of Department of Science and Technology of Guangdong Province and Health Commission of Guangdong Province for chloroquine in the treatment of novel coronavirus pneumonia developed this expert consensus after extensive discussion. It recommended chloroquine phosphate tablet, 500mg twice per day for 10 days for patients diagnosed as mild, moderate and severe cases of novel coronavirus pneumonia and without contraindications to chloroquine.
The Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) first broke out in Wuhan (China) and subsequently spread worldwide. Chloroquine has been sporadically used in treating SARS-CoV-2 infection. Hydroxychloroquine shares the same mechanism of action as chloroquine, but its more tolerable safety profile makes it the preferred drug to treat malaria and autoimmune conditions. We propose that the immunomodulatory effect of hydroxychloroquine also may be useful in controlling the cytokine storm that occurs late-phase in critically ill SARS-CoV-2 infected patients. Currently, there is no evidence to support the use of hydroxychloroquine in SARS-CoV-2 infection.
In Massachusetts, one hospital, Boston Medical Center, said it ordered hydroxychloroquine early in the pandemic and is giving it to suspected coronavirus patients with breathing trouble.
The hospital reviewed emerging information about the use of the drug on the coronavirus in other countries and decided it would be prudent to try it in patients who are displaying signs of respiratory distress, said Dr. Tamar Barlam, chief of BMC’s division of infectious disease. The safety of the drug is well established, she said, and it could reduce the body’s dangerous inflammatory response to the virus. She said more than a dozen patients have been treated with the drug but that it’s too early to say if it has any benefit.
From the comments:
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Massachusetts has had a high caseload for some time now. There has only been one death there. The medical community in Boston is pretty much the best on earth; they are not prone to falling into quackery. While rigorous clinical evaluation of the efficacy of chloroquines is badly needed, it looks like their educated guess may turn out to be right.
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