Sticky -General Covid discussion thread (states, restaurant, wife, older)

[Mikala43]

Originally Posted by markg91359

Just this question:

If recruitment of certain groups for coronavirus vaccine studies is slower than for others why not try an incentive based approach? For example, couldn't large cash payments be offered as a method to recruit volunteers from groups you need more participation from?

I would think something like this would be quick and effective.

Then you get only a certain economic class. I'm not sure how picky they are on variety (tired, can't think of right word).

I would imagine that getting a good poll is similar to getting a good vaccine group.

EX: polls are automatically skewed because of the type of person who will pick up their phone (female, older), to get a true random sampling (found it!) is difficult.

[suzy_q2010]

Originally Posted by markg91359

Just this question:

If recruitment of certain groups for coronavirus vaccine studies is slower than for others why not try an incentive based approach? For example, couldn't large cash payments be offered as a method to recruit volunteers from groups you need more participation from?

I would think something like this would be quick and effective.

Participants are being paid. For minorities who are convinced that they would be abused in a "medical experiment" I am not sure even paying more would induce them to join.

[TakingItEasy]

Listening to Fauci today. This is going to go on for awhile ---don't make any big plans for your 2021 and don't expect that you'll be getting rid of the masks immediately, or even the socially distancing for that matter.

I'd say, as older Americans, we're even more likely to have to keep living with these precautions for awhile. If I were a 20-something, I'd likely be more venturesome and not so worried.

Even when part of the population is vaccinated, the risk remains. And the vaccine success rate may only be something like 70%.

I'd hate to be a kid going to school (elem, high school, college) right now. This may become the new normal for quite awhile. And for folks in their 80's in retirement centers (my parents) - who knows how many more years they have and to think their last ones are spent in semi-seclusion, worrying about anyone around infecting them.

[markg91359]

Originally Posted by suzy_q2010

Participants are being paid. For minorities who are convinced that they would be abused in a "medical experiment" I am not sure even paying more would induce them to join.

I think a $50,000 bonus would get a lot of people to volunteer. What I'm less certain about is whether doing that would somehow create some kind of an ethical issue.

[Mikala43]

Originally Posted by markg91359

I think a $50,000 bonus would get a lot of people to volunteer.

If someone offered me that much it would ensure I wouldn't sign up.

[markg91359]

Originally Posted by Mikala43

If someone offered me that much it would ensure I wouldn't sign up.

YOU wouldn't.....but many probably would. Why not try it or something like it?

[TakingItEasy]

Dr. Anthony Fauci, the government’s top infectious disease expert, said Friday that normal times won’t replace America’s long coronavirus nightmare until deep into 2021, explaining that it will take months to widely administer a vaccine.

The 79-year-old immunologist said he continues to expect a vaccine to be available by the beginning of 2021.

“But by the time you mobilize the distribution of the vaccine and get a majority or more of the population vaccinated and protected, that’s likely not going to happen until the end of 2021,” Fauci told MSNBC. “If you’re talking about getting back to a degree of normality prior to COVID, it’s going to be well into 2021, maybe even towards the end of 2021.”

[NYgal1542]

^^^^^^^^^^ ugh!

[elnrgby]

Originally Posted by suzy_q2010

Adenoviruses are known to cause transverse myelitis:

https://academic.oup.com/cid/article/36/5/550/451768

It has also been reported with SARS-CoV-2:

https://casereports.bmj.com/content/13/8/e236720

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7275163/

Presuming the trial participant's transverse myelitis is due to the vaccine, the question would be how frequently it would happen. Is it one in tens of thousands of doses or one in hundreds of thousands? Would the vaccine cause more cases than infection with the coronavirus? There is no way to know yet.

Well, I was wrong! AstraZeneca has resumed their vaccine trial after the pause of only a few days, despite the case of transverse myelitis (btw, that person received the vaccine, not placebo). They apparently had another study participant diagnosed with multiple sclerosis after starting the trial, though deemed to be unrelated to the vaccine (but MS is also a demyelinating disorder).



Unless the AstraZeneca vaccine proves to be much more effective than the others, I'm not getting that one. Pfizer looks most promising so far. At least 1/5 of their trial participants are black and Latino, so shouldn't be a problem with lack of genetic diversity in the trial either.

[suzy_q2010]

Originally Posted by elnrgby

Well, I was wrong! AstraZeneca has resumed their vaccine trial after the pause of only a few days, despite the case of transverse myelitis (btw, that person received the vaccine, not placebo). They apparently had another study participant diagnosed with multiple sclerosis after starting the trial, though deemed to be unrelated to the vaccine (but MS is also a demyelinating disorder).

Unless the AstraZeneca vaccine proves to be much more effective than the others, I'm not getting that one. Pfizer looks most promising so far. At least 1/5 of their trial participants are black and Latino, so shouldn't be a problem with lack of genetic diversity in the trial either.

I am glad they restarted it. If the transverse myelitis is due to the vaccine there is as yet no way to know how often it would happen. It could be with one in 15,000 doses or one in 150,000 but just showed up in the first 15,000.