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Old 04-10-2020, 05:56 PM
 
Location: Georgia, USA
37,110 posts, read 41,250,908 times
Reputation: 45135

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Quote:
Originally Posted by newtovenice View Post
Yes, I am quite aware of Phase 4.

Which part do you need clarification on?

The part where the American public is used to check for lack of efficacy and additional side effects while being told the drug is PERFECTLY SAFE and WORKS LIKE A CHARM?

No thanks.

People have no clue about ANY of this.
Who has ever claimed any drug is "PERFECTLY SAFE and WORKS LIKE A CHARM"? Link, please.


It appears you do not understand that it would be impossible to conduct drug trials with enough participants to find rare side effects. The cost would be astronomical to find adverse effects that happen to 1 in 100,000 or 1 in 1,000,000 people.

If a drug is not efficacious smaller trials will show that and the drug will never make it to market.
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Old 04-11-2020, 12:33 AM
 
Location: moved
13,646 posts, read 9,708,585 times
Reputation: 23478
Quote:
Originally Posted by newtovenice View Post
I disagree. I think if you are a healthy person with no comorbidities you'd be better off getting exposed. Your body can build its own immunity.
I'd not go that far. Reasonable measures of self-protection are worthwhile for quite literally everyone. The question is, what is reasonable? And how does that depend on our individual circumstances?

Quote:
Originally Posted by craigiri View Post
Often people would ask us why they couldn't take shortcuts "like grand dad did". Given "thinking for themselves", they would have done it....and killed people, and destroyed property.

Our answer was always the same "When Grandpa blew himself up or burned down his farmhouse three hollows over you didn't hear about it. Now we actually count how many people burn themselves up and the statistic say".....
We have to realize that safety isn't free. There is a cost, in inefficiency, in lost profits, in lost productivity. If grandpas died with exorbitant frequency, we'd have a problem. We would need tighter regulation, maybe even rethinking the whole enterprise. But if no one ever dies, and no property is ever destroyed, then arguably the safety-culture is too extreme. It's too high a price to pay.

If no astronauts ever died in space or on the launchpad, that's fantastic in terms of preserving life. But it also means that the rocket is over-engineered and probably too heavy. Some performance-potential is being left on the table.

Quote:
Originally Posted by Chas863 View Post
There seem to be two main trains of thought regarding how we should act with regard to the CV situation.

The first train of thought is that for MOST people, the CV is not a serious threat. Therefore, most people should be allowed to go about their daily activities ...

The second train of thought is that CV is a serious danger to everyone regardless of age or health condition. Therefore, nearly everyone should be required to stay home, ...
Actually, what we hear most often is the shrill whistle of a third train of thought: most people might be asymptomatic, or only moderately symptomatic... yet they're going to infect people who in turn will infect people and so forth, until somebody in that chain of infections dies. Therefore everyone should be quarantined, out of civic duty.
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