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Also, I'm thinking of St. Louis which as a stunning number of restaurant/shopping type districts that go on forever. For example. South Grand, Cherokee Street, Manchester Avenue, Delmar Boulevard, and Euclid Avenue. I mean wow, St. Louis. Maybe because downtown St. Louis has taken a while to come back, these other parts of the city have flourished in a way I don't recall seeing in any other city.
A much, much shorter list might be least urban districts outside of the CBD, lol.
Out of the larger US cities proper, Phoenix has a lot of undeveloped desert within its borders.
In terms of actual neighborhoods, the wooded hillside neighborhoods on the west side of Portland are worth a mention.
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