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Old 03-15-2020, 10:35 AM
 
20,715 posts, read 19,357,373 times
Reputation: 8280

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Quote:
Originally Posted by vision33r View Post
They make all this fancy graphs and maps to show Coronavirus cases but what about influenza? Have we completely ignored it?

https://www.worldometers.info/

Quick facts:
Every year an estimated 290,000 to 650,000 people die in the world due to complications from seasonal influenza (flu) viruses.

This figure corresponds to 795 to 1,781 deaths per day due to the seasonal flu.

98,474 Seasonal flu deaths this year

We keep thinking coronavirus is the biggest killer. It hasn't caught up with the regular flu. I wonder how many people actually have the regular flu and causing the hospitals to mistaken them for coronavirus.

Yes, we should still be careful not to catch any flu but let's put things in perspective too.



Its not the flu. Go to a flu thread where you can apply linear functions.



Send you refutations for peer review. Perhaps they can make use of your brilliant insights.





https://www.thelancet.com/journals/l...260-9/fulltext


Given that 2019-nCoV is no longer contained within Wuhan, other major Chinese cities are probably sustaining localised outbreaks. Large cities overseas with close transport links to China could also become outbreak epicentres, unless substantial public health interventions at both the population and personal levels are implemented immediately. Independent self-sustaining outbreaks in major cities globally could become inevitable because of substantial exportation of presymptomatic cases and in the absence of large-scale public health interventions. Preparedness plans and mitigation interventions should be readied for quick deployment globally.

Last edited by gwynedd1; 03-15-2020 at 10:48 AM..
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Old 03-15-2020, 10:41 AM
 
20,715 posts, read 19,357,373 times
Reputation: 8280
Quote:
Originally Posted by matisse12 View Post
This must be one of the most absurd threads in existence known to man. I have never seen so much misinformation, people posing as pseudo experts, people posing as knowledgeable, people believing the aforementioned people as if they are knowledgeable, and ridiculous statements.

And the complete absurdity of calling this thread 'The Coronavirus Science Thread' when it is anything but that.



Uh yes , people like you for example. The way it works is you are either an expert in a field ,and thus you can speak on your own authority, or the other option is to create a chain of authority by citing reputable sources. For example, I make assertion in vitamin D . I prefer to cite Vieth's work. If you disagree with this then you have absolutely now idea how research papers actually work. A third option is to form an opinion , and offer it as such. You have given prima facie evidence of the value of your opinion.
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Old 03-15-2020, 10:44 AM
 
20,715 posts, read 19,357,373 times
Reputation: 8280
Quote:
Originally Posted by Bluefox View Post
Interesting article about using the “blood of the immune,” an antiquated practice used during the Spanish Influenza pandemic. Any thoughts?

https://www.nbcnews.com/health/healt...ients-n1158476



I think china was using plasma , which ought to contain antibodies. I did not follow it up however. Not sure if its being used elsewhere.
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Old 03-15-2020, 12:27 PM
 
20,715 posts, read 19,357,373 times
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Quote:
Originally Posted by Crazee Cat Lady View Post
An Effective Treatment for Coronavirus (COVID-19)




I have no idea how accurate or scientific this is, but is an interesting read.



I recall the treatment and the suggestion of targeting the PH dependent enzymatic reaction . This treat was said to alkalize intracellular PH. Inhibits bringing it into the cell meant by endosomal I believe.
According to research by the US CDC, chloroquine has strong antiviral effects on SARS coronavirus, both prophylactically and therapeutically. SARS coronavirus has significant similarities to COVID-19. Specifically, the CDC research was completed in primate cells using chloroquine’s well known function of elevating endosomal pH.
Certainly plausible since many reactions are PH dependent .




However med cram was suggesting that it helps zinc get past the lipid barriers as an ionophore where zinc ions inhibit RNA replicase, which is just part of the replication cycle.
"a substance which is able to transport particular ions across a lipid membrane in a cell."


Seems like its a gradient rather than an active transporter....




But which is it? Is it a little of both?
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Old 03-15-2020, 12:37 PM
 
Location: SLC
3,096 posts, read 2,220,033 times
Reputation: 9021
Quote:
Originally Posted by kavm View Post
I never got a response on this. Now, there are reports of a Japanese man testing positive for the second time, after having been cleared. And, Japanese hospitals use 2 negative test to rule out the infection. So, he had 2 negatives at the beginning of March and now a positive again.

https://www3.nhk.or.jp/nhkworld/en/news/20200315_13/

So, either this is a case of false negative(s) or something more. Would like a scientific response.
I have been interested in the type 1 and type 2 error statistics of Covid-19 testing. This paper seems to deal with false positive rates - which seem rather poor.

https://www.unboundmedicine.com/medl...tion/32133832/[Potential_false_positive_rate_among_the_'asymptoma tic_infected_individuals'_in_close_contacts_of_COV ID_19_patients]

The following link refers to a JAMA research letter findings - including discussions of testing errors and indirect methods of transmission...

Study: COVID-19 may spread in several different ways | CIDRAP

Also relevant is the following, which discusses the 're-infection' cases as either false positive/negative and/or virus going dormant. Obviously, reinfection is a secondary threat, but the type 1 and type 2 errors in testing are very important at every stage...

https://www.snopes.com/fact-check/covid-19-reinfection/

Last edited by kavm; 03-15-2020 at 12:53 PM..
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Old 03-15-2020, 01:00 PM
 
Location: NYC
20,550 posts, read 17,697,355 times
Reputation: 25616
The numbers have spiked today, probably due to people being sick have reached out to get tested. What I keep telling people is that under normal circumstances this was about as bad as very contagious flu season. It was in 12-14' I believe we had several episodes of these flu outbreaks around the office. Myself I had the flu and my son had it too, we were both isolated for about 2 weeks. I couldn't go to work, heard a lot of people in the office also gotten the flu too. Some folks had longer duration.

If we compare the number those years, majority of the people over 80% recovered. Many youtube videos are popping out with people who recovered at home with similar symptoms to the normal flu. If that is the case, then your body was able to overcome this virus.

While it killed a lot of people overseas, that needs to be researched just what kind of demographics we're dealing with here. So far, I'm not seeing average Joe or Mary dying from this. It's usually someone who is elderly or have underlying symptoms.
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Old 03-15-2020, 01:22 PM
 
Location: Saint John, IN
11,582 posts, read 6,733,435 times
Reputation: 14786
www.coronavirusnow.com

Global and state stats.
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Old 03-15-2020, 01:30 PM
 
20,715 posts, read 19,357,373 times
Reputation: 8280
Quote:
Originally Posted by CGab View Post
www.coronavirusnow.com

Global and state stats.

We have city-date one now.





https://www.city-data.com/covid-19.html
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Old 03-15-2020, 01:32 PM
 
Location: SLC
3,096 posts, read 2,220,033 times
Reputation: 9021
Quote:
Originally Posted by vision33r View Post
The numbers have spiked today, probably due to people being sick have reached out to get tested. What I keep telling people is that under normal circumstances this was about as bad as very contagious flu season. It was in 12-14' I believe we had several episodes of these flu outbreaks around the office. Myself I had the flu and my son had it too, we were both isolated for about 2 weeks. I couldn't go to work, heard a lot of people in the office also gotten the flu too. Some folks had longer duration.

If we compare the number those years, majority of the people over 80% recovered. Many youtube videos are popping out with people who recovered at home with similar symptoms to the normal flu. If that is the case, then your body was able to overcome this virus.

While it killed a lot of people overseas, that needs to be researched just what kind of demographics we're dealing with here. So far, I'm not seeing average Joe or Mary dying from this. It's usually someone who is elderly or have underlying symptoms.
Why do you insist on pushing your personal flu comparisons, particularly on this Corornavirus Science thread? What part of your post is just your opinion/questions/doubts and what part is science?
Your posts (at least the last two) have been off-topic. Please create a separate thread if you feel the need to push that point of view. Do not corrupt this thread.

If you want science - gwynedd1 posted a Lancet article just a few posts above yours (#91). Read that and think about what the exponential growth means - particularly to the ability of the system (hospital beds, ventilators, medical and support staff). If you still think it is like a flu season - create a thread on that and inform the world.
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Old 03-15-2020, 02:57 PM
 
9,861 posts, read 4,638,421 times
Reputation: 7497
The medical community in France doesn't want to treat coronavirus patients with ibuprofen saying that anti-inflammatories can hamper the body's immune system.


https://bgr.com/2020/03/15/coronavir...reat-symptoms/
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